abstract：:Li Fraumeni Syndrome (LFS) is a rare autosomal disorder characterized by a familial clustering of tumors. Analysis of several series of LFS families have shown that 70% of such families are attributable to germ-line mutations in TP53. We report the case of a patient who had a first degree family antecedent of cancer i...

journal_title：Annales de biologie clinique

authors： Landolsi S,Gharbi O,Zrig M,Gribaa M,Njim L,Zakhama A,Abid A,Frébourg T,Ahmed SB

更新日期：2010-05-01 00:00:00

abstract：:We compared the results of two methods of measurement of HbA(1c) before replacing the current method on Integra 800 by the HPLC method on an apparatus recently put on the market, the G8. The comparative study of the results for 119 patients was carried out. The reproducibility obtained with the G8 method is good with ...

journal_title：Annales de biologie clinique

authors： Szymanowicz A,Neyron MJ

更新日期：2010-03-01 00:00:00

abstract：:Salmonelloses are becoming more frequented. To date, very few cases of aneurisms or vascular grafts infections have been described. We report the rare case of an extradigestive manifestation, due to Salmonella enteritidis affecting a patient with Behçet disease. The biological diagnosis is based on microorganism isola...

journal_title：Annales de biologie clinique

authors： Oudaïna W,Rhissassi B,Lagmouchi M,Aboulmakarim S,Bensaid Y,Zouhdi M

更新日期：2010-01-01 00:00:00

abstract：:The 2007 international consensus about the standardization of HbA(1c) determination and expression of results is progressively implemented in most countries. In France, a common working group of the Société française de biologie clinique (SFBC) and the Société francophone de diabétologie (SFD) has expressed the follow...

journal_title：Annales de biologie clinique

authors： Gillery P,Périer C,Bordas-Fonfrède M,Hue G,Chapelle JP,Vexiau P,Vialettes B

更新日期：2009-11-01 00:00:00

abstract：:Peripheral gangrene with disseminated intravascular coagulation (DIC) during severe Plasmodium falciparum malaria has already been described but is unfrequent. We report here the case of a 62-year-old man admitted in the intensive care unit of our hospital for severe Plasmodium falciparum malaria with disseminated int...

journal_title：Annales de biologie clinique

authors： Tessier-Marteau A,Cruguel Sl,Grand F,Asfar P,Zandecki M,Macchi L

更新日期：2009-09-01 00:00:00

abstract：:It is often reminded that if the ionized calcium is not measured, the interpretation of total calcemia should consider serum albumin. Two formulas are usually employed: ["Corrected" Ca (mmol/L) = Ca measured (mmol/L) + 0.020 or 0.025 (40 - albumin (g/L))]. This adjustment formula arises from works of Payne published i...

journal_title：Annales de biologie clinique

authors： Parent X,Spielmann C,Hanser AM

更新日期：2009-07-01 00:00:00

abstract：:A growing number of clinical practice guidelines (CPG) is published. This is understandable because CPG are the corner stone in the evaluation of professional practices (EPP). One cannot deny that EPP is necessary. However, in order for the EPP to reach their objectives, which are to use our resources better and to im...

journal_title：Annales de biologie clinique

authors： Augereau C,Couaillac JP,De Mouy D,Dézier JF,Fonfrède M,Lepargneur JP,Szymanowicz A,Watine J

更新日期：2009-07-01 00:00:00

abstract：:Inhibins, activins, and anti-Mullerian hormone (AMH) are gonadal dimeric peptides produced in ovaries and testes by homologous cells, granulosa cells and Sertoli cells, respectively. The production of inhibins is driven by FSH, that of AMH may indirectly depends on FSH, while it is down regulated, at least in the male...

journal_title：Annales de biologie clinique

authors： Lahlou N,Bouvattier C,Linglart A,Rodrigue D,Teinturier C

更新日期：2009-05-01 00:00:00

abstract：:Anti-erythrocyte alloimmunization may occur following the transfusion of platelet concentrates, in response to the presence of residual erythrocytes. Immunization against RH1 (D) antigen is the most frequent, but transfusion of RH1 compatible platelet concentrates is not always possible because of supply constraints. ...

journal_title：Annales de biologie clinique

authors： Duboeuf S,Flourié F,Courbil R,Oriol P,Benamara A,Chartier M,Rigal E,Garraud O

更新日期：2009-05-01 00:00:00

abstract：:Our study has for aim to describe the practices of screening of the gestational diabetes mellitus. Screening test was realised at 61% of the women included in the study. The HGPO in 50 g was prescribed in 47% of the cases, a single fasting blood glucose in 28% of the cases; 13,4% of the detected women had a glycaemia ...

journal_title：Annales de biologie clinique

authors： Bouhsain S,Dami A,Elannaz H,Guelzim K,Baba H,Elhassani MM,Mechtani S,Tellal S,Dhayni M,Moussaoui D,Derouiche M

更新日期：2009-03-01 00:00:00

abstract：:The aim of this study is to present an evaluation of HbA(1c) Assay on Architect CI8200 (Abbott Diagnostic). The measurement includes Hb assay by colorimetry and HbA(1c) by immunoturbidimetry. The percentage of HbA(1c) is the report HbA(1c)/complete Hb with a conversion coefficient. Repetability (n = 30; CV: 1.15-1.91%...

journal_title：Annales de biologie clinique

authors： Beaune G,Ducruet J,Jund J,Favre S

更新日期：2009-01-01 00:00:00

abstract：:Cystic fibrosis (CF), is the most common life-shortening autosomal recessive disorder in Caucasians. It is caused by mutations in a single gene on the long arm of chromosome 7 that encodes the cystic fibrosis transmembrane conductance regulator (CFTR) protein. CF is characterized by abnormal Na+ and Cl- ion transport ...

journal_title：Annales de biologie clinique

authors： Pongnimitprasert N,El-Benna J,Foglietti MJ,Gougerot-Pocidalo MA,Bernard M,Braut-Boucher F

更新日期：2008-11-01 00:00:00

abstract：:The analysis of longitudinal series of tumour markers during chemotherapy in patients with germ cells tumors is not easy. The purpose of this work is to present various characteristic profiles of the evolution of serum human chorionic gonadotropin during chemotherapy and review the modalities of the dynamic interpreta...

journal_title：Annales de biologie clinique

authors： Riedinger JM,Eche N,Fargeot P

更新日期：2008-09-01 00:00:00

abstract：:The search for sperm is part of the examinations wich may be prescribed, following a request of jucicial services, in case of a suspicion of sexual assault. This article applies to detail how the different phases, pre-analytical, analytical and post-analytical, must be absolutely adhered to so that the biologist, expe...

journal_title：Annales de biologie clinique

authors： Laudat A,Lecourbe K

更新日期：2008-09-01 00:00:00

abstract：:Urinary ammonium excretion is the best parameter to quantify net acid excretion by the kidney. As measurement of ammonium excretion is not routinely available, clinicians use formulas to estimate NH(4)+ excretion. However, the measurement of urinary NH(4)+ concentration can be performed by an automatically method, whi...

journal_title：Annales de biologie clinique

authors： Szmidt-Adjidé V,Vanhille P

更新日期：2008-07-01 00:00:00

abstract：:HbA(1c) assay by high pressure liquid chromatography remains submitted to interferences, among which that of labile HbA(1c) in 1 to 2% of samples. We have evaluated the interference of labile HbA(1c) on HbA(1c) assay using Variant II analyzer (Biorad), by in vitro formation of labile glycated haemoglobin and by evalua...

journal_title：Annales de biologie clinique

authors： Szymezak J,Leroy N,Lavalard E,Gillery P

更新日期：2008-07-01 00:00:00

abstract：:Human embryonic stem cells (hESC) are obtained from the inner cell mass from the early embryo at blastocyste stage. Derived in cell lines for the first time in 1998, they can be maintained in culture in an undifferentiated state indefinitely under certain conditions. Two essential properties characterize hESC: pluripo...

journal_title：Annales de biologie clinique

authors： Tondeur S,Assou S,Nadal L,Hamamah S,De Vos J

更新日期：2008-05-01 00:00:00

abstract：:Cystatin C is a low molecular weight-protein, which may replace creatinine for the evaluation of renal function, particularly in the clinical settings where the relationship between creatinine production and muscular mass impairs the clinical performance of creatinine. This paper intends to summarize the current knowl...

journal_title：Annales de biologie clinique

authors： Séronie-Vivien S,Delanaye P,Pieroni L,Mariat C,Froissart M,Cristol JP,Groupe de travail \Biologie des fonctions rénales et de l'insuffisance rénale\ de la SFBC.

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:probiotic agents are increasingly used as over the counter drugs for the treatment of a variety of inflammatory and infectious conditions. The rationale of their use seems to restore a friendly bacterial flora in the gut. Complications of probiotic use, although rarely reported, can occur. OBSERVATION:we de...

journal_title：Annales de biologie clinique

authors： Zein EF,Karaa S,Chemaly A,Saidi I,Daou-Chahine W,Rohban R

更新日期：2008-03-01 00:00:00

abstract：:In our societies, the increase of the frequency of the diseases of overweight, in particular obesity, diabetes type 2 and metabolic syndrome, coincides with that of the urinary lithiasis. Like the lithiasic disease, the metabolic syndrome or syndrome X is multi-factor. Several epidemiological studies were interested i...

journal_title：Annales de biologie clinique

authors： Zerifi R,Bahlous A,Marakchi O,Daudon M,Bartagi Z,Abdelmoula J

更新日期：2008-01-01 00:00:00

abstract：:The performance of the HemoCue apparatus in the diagnosis of anaemia in pregnancy was evaluated using the HemoCue Hb 301 and the HemoCue Hb 201+ apparatus. The HemoCue Hb 201 + was considered as the reference method in this study. Two hundred and thirty six pregnant women attending the University Teaching Hospital in ...

journal_title：Annales de biologie clinique

authors： Tayou Tagny C,Kouam L,Mbanya D

更新日期：2008-01-01 00:00:00

abstract：:Our study was carried out at a family from the Sahel (Tunisia). The father (index case) and his two children (son and daughter). The father beta-glucocerebrosidase (GCB) activity showing a deficit. These biochemical analyses are supplemented by molecular studies: enzymatic digestion and the direct sequencing. Two muta...

journal_title：Annales de biologie clinique

authors： Dandana A,Ferchichi S,Khedhiri S,Chkioua L,Jaidane Z,Monastiri K,Ben Khelifa S,Ben Mansour R,Maire I,Froissart R,Bonnet V,Laradi S,Miled A

更新日期：2007-11-01 00:00:00

abstract：AIMS:To evaluate the effect of the physical activity on bone turnover in young male soccer players at the Tanner's stage of 1-2. MATERIAL AND METHODS:61 young soccer players (13,4 +/- 0,3 years old) who actively participated in soccer since 3,7 +/- 0,7 years were compared to 60 age and sex- matched non active subjects...

journal_title：Annales de biologie clinique

authors： Kalaï E,Bahlous A,Nbigh A,Sahli H,Sellami S,Abdelmoula J

更新日期：2007-09-01 00:00:00

abstract：:In biochemistry laboratory, monoclonal immunoglobulins are frequently found. They can lead to analytical interferences which are difficult to anticipate. In this case reports, a monoclonal immunoglobulin M with cryoglobulin effect has been responsible of false result of protein electrophoresis because of the whole pre...

journal_title：Annales de biologie clinique

authors： Oliver M,Ragot C,Savini H,Chianéa D,Navarro L,Moalic JL

更新日期：2007-09-01 00:00:00

abstract：:Total plasma homocysteine emerged in the past few years as an independent risk factor for cardiovascular diseases. This test is now currently prescribed for the diagnosis of unexplained thrombosis in young adults or recurrent thrombosis in patients with arteriopathy. This sulphured amino-acid is an important intermedi...

journal_title：Annales de biologie clinique

authors： Belkhiria MN,Ducros V,Harzallah K,Jarraya F,Cordonnier D,Favier A,Achour A

更新日期：2007-07-01 00:00:00

abstract：:Panton-Valentine leukocidin-producing (PVL) Staphylococcus aureus is responsible for a highly lethal necrotizing pneumonia, which occurs predominantly in young immunocompetent patients. Hemoptysis and leucopenia often occur but are not always present. Detection of PVL gene on S. aureus strains responsible for pneumoni...

journal_title：Annales de biologie clinique

authors： Dubrous P,Cuguillère A,Gendrot A,Koeck JL

更新日期：2007-05-01 00:00:00

abstract：:The measurement of CDT (Carbohydrate Deficient Transferrin) is an essential biological tool in the diagnosis and follow-up of alcohol abuse. It is also employed as a marker of abstinence for the restitution of driving licences. However, the precision of measurement, and the between laboratory homogeneity of the result...

journal_title：Annales de biologie clinique

authors： Boehrer JL,Cano Y,Capolaghi B,Desch G,Dosbaa I,Estepa L,Hennache B,Schellenberg F

更新日期：2007-03-01 00:00:00

abstract：:Mucopolysaccharidosis type IV A (MPS IV A) is an autosomal recessive disorder resulting from the deficient activity of the lysosomal enzyme, N-acetylgalactosamine-6-sulfate sulfatase (GALNS) and the progressive lysosomal accumulation of keratane sulfate. Clinically, the MPS IV A differs from the other MPS by the local...

journal_title：Annales de biologie clinique

authors： Khedhiri S,Chkioua L,Ferchichi S,Bouzidi H,Haj Khelil A,Ben Mansour R,Kassab A,M'dallah S,Chaabouni M,Jrad T,Ben Chibani J,Miled A,Laradi S

更新日期：2007-01-01 00:00:00

abstract：:Evaluation of the neonates for jaundice and kernicterus is indispensable when early hospital discharge has become standard practice. Transcutaneous bilirubin (TcB) measurement is an advantageous option because of its non-invasive nature and the possibility of its use near the patient. The point of care device BiliChec...

journal_title：Annales de biologie clinique

authors： Carceller AM,Delvin E,Gonthier M,Grégoire MC,Cousineau J,Alexandrov L

更新日期：2006-11-01 00:00:00

abstract：:The non-secreting myeloma is a rare form of myeloma. Its association with a nephrotic syndrome is exceptional. The observation which we report below described the history of a 66 years old patient who presents a non-secreting myeloma revealed by a nephrotic syndrome. Various assumptions on the mechanism of no excretio...

journal_title：Annales de biologie clinique

authors： Ouzzif Z,Benyahia M,Doghmi K,Oualim Z,Derouiche M

更新日期：2006-09-01 00:00:00

abstract：:The neuropathies associated with monoclonal IgM gammopathy reacted with glycoconjugated targets on a very antigenic epitope on the sulfated glucuronic glycolipids corresponding to SGPG and SGLPG (sulfoglucuronyl paragloboside and sulfoglucuronyl lactosaminyl paragloboside), myelin-associated glycoprotein (MAG) and sul...

journal_title：Annales de biologie clinique

authors： Caudie C,Kaygisiz F,Jaquet P,Petiot P,Gonnaud PM,Antoine JC,Vial C

更新日期：2006-07-01 00:00:00

abstract：:Elderly patients are at high risk of over-anticoagulation and of haemorrhagic risk when on warfarin, especially during treatment induction. In Charles Foix Hospital, a 800-bed geriatric hospital, we specifically developed for in-patients older than 70 years (target INR 2.5) a simple low-dose warfarin induction regimen...

journal_title：Annales de biologie clinique

authors： Siguret V,N'Guyen A,Harboun M,Chevallier A,Pautas E,Gouin-Thibault I,Berigaud S

更新日期：2006-05-01 00:00:00

abstract：:Acute leukemia of megakaryocyte lineage (AML-7) is a rare entity defined by a blastic proliferation of which a part (>or= 50%) is represented by megakaryoblasts. We report the case of a 95 year old woman presenting a AML-7 secondary to a myelodysplastic syndrome (MDS), that represents an unusual form of MDS acutisatio...

journal_title：Annales de biologie clinique

authors： Smadja DM,Gisselbrecht M,Valensi F,Mossafa H,Darnige L

更新日期：2006-03-01 00:00:00

abstract：:The oculo-cerebro-renal syndrome of Lowe is a rare X-linked disorder, caused by the inositol biphosphate 5-phosphatase deficiency, localized to the Golgi complex. Several mutations were reported in patient's OCRL gene leading to enzyme deficiency. We report a Moroccan case of OCRL syndrome of Lowe with a neo mutation ...

journal_title：Annales de biologie clinique

authors： Chabaâ L,Monnier N,Dahri S,Jorio M,Lunardi J,Chabraoui L

更新日期：2006-01-01 00:00:00

abstract：:The aim of this study was to evaluate the automated urine test strip analyzer Aution Max AX 4280 which uses strips able to measure 12 urinary parameters. For precision study, we considered glucose, protein, blood, leukocytes, nitrite, and pH and the four first were compared with usual methods: chemical measurement or ...

journal_title：Annales de biologie clinique

authors： Steinmetz J,Henny J,Gueguen R

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND AND AIM:Cotinine is a very reliable index for the estimation of active or passive smoking. Sampling from a single urine void is well accepted by smokers who are willing to stop. It is not possible to exclude modification of urine cotinine according to beverage intake. The aim of this study was to determine i...

journal_title：Annales de biologie clinique

authors： Jacob N,Berny C,Boyer JC,Capolaghi B,de l'homme G,Desch G,Garelik D,Houdret N,Le Moel G,Moulsma M,Plantin-Carrenard E,Société française de biologie clinique.,Société française de toxicologie analytique - médecins tabacologues \S

更新日期：2005-09-01 00:00:00

abstract：:We evaluated a rapid and semi-quantitative C-Reactive Protein test on whole blood, the Actim CRP (Fumouze). Based on immuno-chromatography technology, this test ranked the blood sample in four groups: < 10 mg/L, 10-40 mg/L, 40-80 mg/L and > 80 mg/L. This evaluation finds an excellent repeatability, the absence of hook...

journal_title：Annales de biologie clinique

authors： Evrard B,Roszyk L,Fattal S,Dastugue B,Sapin V

更新日期：2005-09-01 00:00:00

abstract：:Thermal burns result in severe electrolytes disturbances which are life-threatening when the percentage of burnt body surface area (BSA) is above 20% in adults and 10% in children. If electrolytes disturbances are often mentioned in the physiopathology of burns, they are less documented in the daily practice of the fo...

journal_title：Annales de biologie clinique

authors： Hauhouot-Attoungbre ML,Mlan WC,Edjeme NA,Ahibo H,Vilasco B,Monnet D

更新日期：2005-07-01 00:00:00

abstract：:The purpose of this transverse prospective study was to determine blood nutritional, immunity and inflammatory proteins change in vitamin A deficiency in children of school-age (262 children, aged 7 to 15 years). Blood vitamin A has been determined by HPLC with UV detection. Proteins have been measured by radial immun...

journal_title：Annales de biologie clinique

authors： Yapi HF,Ahiboh H,Ago K,Aké M,Monnet D

更新日期：2005-05-01 00:00:00

abstract：:Serum digoxin measurement is often performed in medical laboratories. A professional association specialized in quality control, based in Lyon, has been organizing punctual controls of medication measurement for the past ten years. The results are analysed in term of intra and inter-technique precision, difference bet...

journal_title：Annales de biologie clinique

authors： Mandy M,Manchon M,Meley R,Eynard JC,Grafmeyer D

更新日期：2005-05-01 00:00:00